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Research Areas: Asymmetric Catalysis
Asymmetric Catalysis
Catalysis projects emphasize the design and development of strategic asymmetric C-C bond constructions.
The development of catalytic asymmetric aldol addition and Claisen rearrangement reactions have been
primary goals in our group. These investigations have culminated in the development of both Lewis acid-
and Lewis base-catalyzed acyl halide-aldehyde cyclocondensation (AAC) reactions and asymmetric olefin
isomerization-Claisen rearrangement (ICR) reactions. Novel variants of the venerable Diels-Alder
cycloaddition and Ireland ester-enolate Claisen rearrangement are currently under development.
The development of catalytic asymmetric aldol addition and Claisen rearrangement reactions have been
primary goals in our group. These investigations have culminated in the development of both Lewis acid-
and Lewis base-catalyzed acyl halide-aldehyde cyclocondensation (AAC) reactions and asymmetric olefin
isomerization-Claisen rearrangement (ICR) reactions. Novel variants of the venerable Diels-Alder
cycloaddition and Ireland ester-enolate Claisen rearrangement are currently under development.
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Asymmetric Catalysis New Reaction Discovery Complex Molecule Synthesis